Procedural sedation

Agents have various properties: analgesia, sedation, amnesia, dissociation
Usually best to start on the lower end of dosing and titrate to effect
Etomidate 0.1-0.3mg/kg IV
Fentanyl 1-2mcg/kg IV AND Versed 0.02mg/kg IV good for ortho/lacs/adults
Ketamine (dissociative agent) 1-2mg/kg IV OR 4mg/kg IM
            -Agent of choice for peds as pts do not lose airway reflexes.
            -Increases airway secretions.  Some give atropine 0.02mg/kg in same syringe.
                        -May also use glycopyrrolate (Robinul)
            -Emergence reactions are more common in adults.  May decrease with Versed.
Methohexital (Brevital) 1mg/kg IV is a great drug.  Rapid onset and wears off in 2-10min.
Narcan 0.4mg IV (peds: 0.05mg/kg IV).  Lasts 1-2hrs.
Flumazenil 0.2mg IV (peds 0.01mg/kg IV).  Beware seizures in pts with known d/o.